YML065W

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Systematic name YML065W
Gene name ORC1
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:142210..144954


Description of YML065W: Largest subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; may be phosphorylated by Cdc28p[1][2]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [1] [3]

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References

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  1. ↑ 1.0 1.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  2. ↑ Bell SP (2002) The origin recognition complex: from simple origins to complex functions. Genes Dev 16(6):659-72 SGD PMID 11914271
  3. ↑ submitted by Jeff Ubersax on 2004-01-29

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