YLR394W

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Systematic name YLR394W
Gene name CST9
Aliases ZIP3
Feature type ORF, Verified
Coordinates Chr XII:907950..909398


Description of YLR394W: SUMO E3 ligase; required for synaptonemal complex formation; localizes to synapsis initiation sites on meiotic chromosomes; potential Cdc28p substrate[1][2]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]


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References

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  1. Cheng CH, et al. (2006) SUMO modifications control assembly of synaptonemal complex and polycomplex in meiosis of Saccharomyces cerevisiae. Genes Dev 20(15):2067-81 SGD PMID 16847351
  2. Agarwal S and Roeder GS (2000) Zip3 provides a link between recombination enzymes and synaptonemal complex proteins. Cell 102(2):245-55 SGD PMID 10943844
  3. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  4. submitted by Jeff Ubersax on 2004-01-29

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