YPL215W

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Systematic name YPL215W
Gene name CBP3
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:147416..148423
Primary SGDID S000006136


Description of YPL215W: Mitochondrial protein required for assembly of cytochrome bc1 complex; forms a complex with Cbp6p that binds to mt ribosomes near the polypeptide tunnel exit and promotes efficient translation of the COB mRNA; Cbp3p-Cbp6p complex also interacts with newly synthesized cytochrome b (Cobp) and Cbp4p to promote assembly of Cobp into the cytochrome bc1 complex[1][2][3]




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References

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  1. Gruschke S, et al. (2011) Cbp3-Cbp6 interacts with the yeast mitochondrial ribosomal tunnel exit and promotes cytochrome b synthesis and assembly. J Cell Biol 193(6):1101-14 SGD PMID 21670217
  2. Kronekova Z and Rodel G (2005) Organization of assembly factors Cbp3p and Cbp4p and their effect on bc(1) complex assembly in Saccharomyces cerevisiae. Curr Genet 47(4):203-12 SGD PMID 15759116
  3. Shi G, et al. (2001) Identification of functional regions of Cbp3p, an enzyme-specific chaperone required for the assembly of ubiquinol-cytochrome c reductase in yeast mitochondria. Biochim Biophys Acta 1506(2):103-16 SGD PMID 11522252

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