YEL034W
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| Systematic name | YEL034W |
| Gene name | HYP2 |
| Aliases | TIF51A, eIF-5A, eIF5A |
| Feature type | ORF, Verified |
| Coordinates | Chr V:85676..86149 |
| Primary SGDID | S000000760 |
Description of YEL034W: Translation elongation factor eIF-5A that may function in translation initiation; similar to and functionally redundant with Anb1p; structural homolog of bacterial EF-P; undergoes an essential hypusination modification[1][2][3][4][5][6]
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References
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- ↑ Gregio AP, et al. (2009) eIF5A has a function in the elongation step of translation in yeast. Biochem Biophys Res Commun 380(4):785-90 SGD PMID 19338753
- ↑ Henderson A and Hershey JW (2011) Eukaryotic translation initiation factor (eIF) 5A stimulates protein synthesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 108(16):6415-9 SGD PMID 21451136
- ↑ Saini P, et al. (2009) Hypusine-containing protein eIF5A promotes translation elongation. Nature 459(7243):118-21 SGD PMID 19424157
- ↑ Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 SGD PMID 8314769
- ↑ Valentini SR, et al. (2002) Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 160(2):393-405 SGD PMID 11861547
- ↑ Zanelli CF, et al. (2006) eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348(4):1358-66 SGD PMID 16914118
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