YJL156C

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Systematic name YJL156C
Gene name SSY5
Aliases
Feature type ORF, Verified
Coordinates Chr X:128949..126886


Description of YJL156C: Probable serine protease of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that regulate expression of amino acid permease genes[1][2][3]




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References

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  1. Poulsen P, et al. (2006) Mapping of an internal protease cleavage site in the Ssy5p component of the amino acid sensor of Saccharomyces cerevisiae and functional characterization of the resulting pro- and protease domains by gain-of-function genetics. Eukaryot Cell 5(3):601-8 SGD PMID 16524914
  2. Forsberg H, et al. (2001) The role of the yeast plasma membrane SPS nutrient sensor in the metabolic response to extracellular amino acids. Mol Microbiol 42(1):215-28 SGD PMID 11679080
  3. Forsberg H and Ljungdahl PO (2001) Genetic and biochemical analysis of the yeast plasma membrane Ssy1p-Ptr3p-Ssy5p sensor of extracellular amino acids. Mol Cell Biol 21(3):814-26 SGD PMID 11154269

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