YIL124W
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| Systematic name | YIL124W |
| Gene name | AYR1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IX:126204..127097 |
Description of YIL124W: NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles, ER, and mitochondrial outer membrane; involved in phosphatidic acid biosynthesis; required for spore germination; capable of metabolizing steroid hormones[1][2][3]
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References
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- ↑ Zahedi RP, et al. (2006) Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Mol Biol Cell 17(3):1436-50 SGD PMID 16407407
- ↑ Vico P, et al. (2002) Dehydroepiandrosterone (DHEA) metabolism in Saccharomyces cerevisiae expressing mammalian steroid hydroxylase CYP7B: Ayr1p and Fox2p display 17beta-hydroxysteroid dehydrogenase activity. Yeast 19(10):873-86 SGD PMID 12112241
- ↑ Athenstaedt K and Daum G (2000) 1-Acyldihydroxyacetone-phosphate reductase (Ayr1p) of the yeast Saccharomyces cerevisiae encoded by the open reading frame YIL124w is a major component of lipid particles. J Biol Chem 275(1):235-40 SGD PMID 10617610
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