YDR470C
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Systematic name | YDR470C |
Gene name | UGO1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr IV:1401214..1399706 |
Primary SGDID | S000002878 |
Description of YDR470C: Outer membrane component of the mitochondrial fusion machinery; binds directly to Fzo1p and Mgm1p and thus links these two GTPases during mitochondrial fusion; facilitates dimerization of Fzo1p during fusion[1][2][3]
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References
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- ↑ Anton F, et al. (2011) Ugo1 and Mdm30 act sequentially during Fzo1-mediated mitochondrial outer membrane fusion. J Cell Sci 124(Pt 7):1126-35 SGD PMID 21385840
- ↑ Sesaki H and Jensen RE (2001) UGO1 encodes an outer membrane protein required for mitochondrial fusion. J Cell Biol 152(6):1123-34 SGD PMID 11257114
- ↑ Sesaki H and Jensen RE (2004) Ugo1p links the Fzo1p and Mgm1p GTPases for mitochondrial fusion. J Biol Chem 279(27):28298-303 SGD PMID 15087460
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