YIL050W

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Systematic name YIL050W
Gene name PCL7
Aliases
Feature type ORF, Verified
Coordinates Chr IX:258912..259769


Description of YIL050W: Pho85p cyclin of the Pho80p subfamily, forms a functional kinase complex with Pho85p which phosphorylates Mmr1p and is regulated by Pho81p; involved in glycogen metabolism, expression is cell-cycle regulated[1][2][3]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]


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References

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  1. Wang Z, et al. (2001) The yeast cyclins Pc16p and Pc17p are involved in the control of glycogen storage by the cyclin-dependent protein kinase Pho85p. FEBS Lett 506(3):277-80 SGD PMID 11602261
  2. Lee M, et al. (2000) Regulation of the Pcl7-Pho85 cyclin-cdk complex by Pho81. Mol Microbiol 38(2):411-22 SGD PMID 11069666
  3. Measday V, et al. (1997) A family of cyclin-like proteins that interact with the Pho85 cyclin-dependent kinase. Mol Cell Biol 17(3):1212-23 SGD PMID 9032248
  4. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  5. submitted by Jeff Ubersax on 2004-01-27

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