YHR081W

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Systematic name YHR081W
Gene name LRP1
Aliases RRP47, YC1D
Feature type ORF, Verified
Coordinates Chr VIII:267540..268094


Description of YHR081W: Substrate-specific nuclear cofactor for exosome activity in the processing of stable RNAs; required for telomere length maintenance; homolog of mammalian nuclear matrix protein C1D involved in regulation of DNA repair and recombination[1][2][3]




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References

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  1. Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
  2. Mitchell P, et al. (2003) Rrp47p is an exosome-associated protein required for the 3' processing of stable RNAs. Mol Cell Biol 23(19):6982-92 SGD PMID 12972615
  3. Erdemir T, et al. (2002) Saccharomyces cerevisiae C1D is implicated in both non-homologous DNA end joining and homologous recombination. Mol Microbiol 46(4):947-57 SGD PMID 12421302

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