YML036W

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Systematic name YML036W
Gene name CGI121
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:205642..206293
Primary SGDID S000004500


Description of YML036W: Component of the EKC/KEOPS complex with Bud32p, Kae1p, Pcc1p, and Gon7p; EKC/KEOPS complex is required for t6A tRNA modification and may have roles in telomere maintenance and transcription; Cgi121p is dispensable for tRNA modification[1][2][3]




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References

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  1. Downey M, et al. (2006) A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator. Cell 124(6):1155-68 SGD PMID 16564010
  2. Kisseleva-Romanova E, et al. (2006) Yeast homolog of a cancer-testis antigen defines a new transcription complex. EMBO J 25(15):3576-85 SGD PMID 16874308
  3. Srinivasan M, et al. (2010) The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A. EMBO J () SGD PMID 21183954

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