YGL136C

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Systematic name YGL136C
Gene name MRM2
Aliases
Feature type ORF, Verified
Coordinates Chr VII:253864..252902


Description of YGL136C: Mitochondrial 21S rRNA methyltransferase, required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ[1][2]




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References

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  1. Bonnerot C, et al. (2003) Functional redundancy of Spb1p and a snR52-dependent mechanism for the 2'-O-ribose methylation of a conserved rRNA position in yeast. Mol Cell 12(5):1309-15 SGD PMID 14636587
  2. Pintard L, et al. (2002) MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase. EMBO J 21(5):1139-47 SGD PMID 11867542

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