YGL122C

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Systematic name YGL122C
Gene name NAB2
Aliases
Feature type ORF, Verified
Coordinates Chr VII:280529..278952


Description of YGL122C: Nuclear polyadenylated RNA-binding protein; autoregulates mRNA levels; related to human hnRNPs; has nuclear localization signal sequence that binds to Kap104p; required for poly(A) tail length control and nuclear mRNA export[1][2][3][4][5][6]




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References

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  1. Roth KM, et al. (2005) The nuclear exosome contributes to autogenous control of NAB2 mRNA levels. Mol Cell Biol 25(5):1577-85 SGD PMID 15713618
  2. Hector RE, et al. (2002) Dual requirement for yeast hnRNP Nab2p in mRNA poly(A) tail length control and nuclear export. EMBO J 21(7):1800-10 SGD PMID 11927564
  3. Green DM, et al. (2002) Nab2p is required for poly(A) RNA export in Saccharomyces cerevisiae and is regulated by arginine methylation via Hmt1p. J Biol Chem 277(10):7752-60 SGD PMID 11779864
  4. Truant R, et al. (1998) Identification and functional characterization of a novel nuclear localization signal present in the yeast Nab2 poly(A)+ RNA binding protein. Mol Cell Biol 18(3):1449-58 SGD PMID 9488461
  5. Anderson JT, et al. (1993) NAB2: a yeast nuclear polyadenylated RNA-binding protein essential for cell viability. Mol Cell Biol 13(5):2730-41 SGD PMID 8474438
  6. Wilson SM, et al. (1994) Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae. J Cell Biol 127(5):1173-84 SGD PMID 7962083

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