YPR074C

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Systematic name YPR074C
Gene name TKL1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:694838..692796
Primary SGDID S000006278


Description of YPR074C: Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids[1][2]




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References

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  1. Sundstrom M, et al. (1993) Yeast TKL1 gene encodes a transketolase that is required for efficient glycolysis and biosynthesis of aromatic amino acids. J Biol Chem 268(32):24346-52 SGD PMID 8226984
  2. Walfridsson M, et al. (1995) Xylose-metabolizing Saccharomyces cerevisiae strains overexpressing the TKL1 and TAL1 genes encoding the pentose phosphate pathway enzymes transketolase and transaldolase. Appl Environ Microbiol 61(12):4184-90 SGD PMID 8534086

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