YPL219W

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Systematic name YPL219W
Gene name PCL8
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:136750..138228
Primary SGDID S000006140


Description of YPL219W: Cyclin, interacts with Pho85p cyclin-dependent kinase (Cdk) to phosphorylate and regulate glycogen synthase, also activates Pho85p for Glc8p phosphorylation[1][2][3][4]




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References

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  1. Huang D, et al. (1998) Cyclin partners determine Pho85 protein kinase substrate specificity in vitro and in vivo: control of glycogen biosynthesis by Pcl8 and Pcl10. Mol Cell Biol 18(6):3289-99 SGD PMID 9584169
  2. Measday V, et al. (1997) A family of cyclin-like proteins that interact with the Pho85 cyclin-dependent kinase. Mol Cell Biol 17(3):1212-23 SGD PMID 9032248
  3. Tan YS, et al. (2003) Pho85 phosphorylates the Glc7 protein phosphatase regulator Glc8 in vivo. J Biol Chem 278(1):147-53 SGD PMID 12407105
  4. Wilson WA, et al. (2002) Analysis of respiratory mutants reveals new aspects of the control of glycogen accumulation by the cyclin-dependent protein kinase Pho85p. FEBS Lett 515(1-3):104-8 SGD PMID 11943203

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