YOR281C

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Systematic name YOR281C
Gene name PLP2
Aliases
Feature type ORF, Verified
Coordinates Chr XV:847129..846269
Primary SGDID S000005807


Description of YOR281C: Essential protein that interacts with the CCT (chaperonin containing TCP-1) complex to stimulate actin folding; has similarity to phosducins; null mutant lethality is complemented by mouse phosducin-like protein MgcPhLP[1][2][3][4]




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References

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  1. Dekker C, et al. (2008) The interaction network of the chaperonin CCT. EMBO J 27(13):1827-39 SGD PMID 18511909
  2. Flanary PL, et al. (2000) Functional analysis of Plp1 and Plp2, two homologues of phosducin in yeast. J Biol Chem 275(24):18462-9 SGD PMID 10749875
  3. Lopez P, et al. (2003) A novel germ line-specific gene of the phosducin-like protein (PhLP) family. A meiotic function conserved from yeast to mice. J Biol Chem 278(3):1751-7 SGD PMID 12424248
  4. McCormack EA, et al. (2009) Yeast phosducin-like protein 2 acts as a stimulatory co-factor for the folding of actin by the chaperonin CCT via a ternary complex. J Mol Biol 391(1):192-206 SGD PMID 19501098

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