YOL054W
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| Systematic name | YOL054W |
| Gene name | PSH1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:228614..229834 |
| Primary SGDID | S000005415 |
Description of YOL054W: E3 ubiquitin ligase that mediates poyubiquitination and degradation of centromere-binding protein Cse4p and prevents Cse4p from mislocalizing to euchromatin; ubiquitylation of Cse4p may be antagonized by Scm3p[1][2]
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References
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- ↑ Hewawasam G, et al. (2010) Psh1 Is an E3 Ubiquitin Ligase that Targets the Centromeric Histone Variant Cse4. Mol Cell 40(3):444-54 SGD PMID 21070970
- ↑ Ranjitkar P, et al. (2010) An E3 Ubiquitin Ligase Prevents Ectopic Localization of the Centromeric Histone H3 Variant via the Centromere Targeting Domain. Mol Cell 40(3):455-64 SGD PMID 21070971
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