YOL043C

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Systematic name YOL043C
Gene name NTG2
Aliases SCR2
Feature type ORF, Verified
Coordinates Chr XV:249534..248392
Primary SGDID S000005403


Description of YOL043C: DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair, localizes to the nucleus; sumoylated[1][2][3]




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References

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  1. Alseth I, et al. (1999) The Saccharomyces cerevisiae homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient repair of spontaneous and induced oxidative DNA damage in yeast. Mol Cell Biol 19(5):3779-87 SGD PMID 10207101
  2. Griffiths LM, et al. (2009) Dynamic compartmentalization of base excision repair proteins in response to nuclear and mitochondrial oxidative stress. Mol Cell Biol 29(3):794-807 SGD PMID 19029246
  3. Meadows KL, et al. (2003) Characterization of AP lyase activities of Saccharomyces cerevisiae Ntg1p and Ntg2p: implications for biological function. Nucleic Acids Res 31(19):5560-7 SGD PMID 14500818

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