YGL016W

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Systematic name YGL016W
Gene name KAP122
Aliases PDR6
Feature type ORF, Verified
Coordinates Chr VII:461671..464916


Description of YGL016W: Karyopherin beta, responsible for import of the Toa1p-Toa2p complex into the nucleus; binds to nucleoporins Nup1p and Nup2p; may play a role in regulation of pleiotropic drug resistance[1][2]




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References

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  1. Titov AA and Blobel G (1999) The karyopherin Kap122p/Pdr6p imports both subunits of the transcription factor IIA into the nucleus. J Cell Biol 147(2):235-46 SGD PMID 10525531
  2. Chen WN, et al. (1991) The DNA sequencing of the 17 kb HindIII fragment spanning the LEU1 and ATE1 loci on chromosome VII from Saccharomyces cerevisiae reveals the PDR6 gene, a new member of the genetic network controlling pleiotropic drug resistance. Yeast 7(3):287-99 SGD PMID 1882553

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