YLL049W

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Systematic name YLL049W
Gene name LDB18
Aliases
Feature type ORF, Verified
Coordinates Chr XII:40666..41205
Primary SGDID S000003972


Description of YLL049W: Component of the dynactin complex, which is required for dynein activity; null mutant exhibits defects in nuclear migration and spindle orientation and has reduced affinity for alcian blue dye; has homology to mammalian dynactin subunit p24[1][2][3]




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References

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  1. Amaro IA, et al. (2008) The Saccharomyces cerevisiae Homolog of p24 Is Essential for Maintaining the Association of p150Glued With the Dynactin Complex. Genetics 178(2):703-9 SGD PMID 18245366
  2. Corbacho I, et al. (2005) A genome-wide screen for Saccharomyces cerevisiae nonessential genes involved in mannosyl phosphate transfer to mannoprotein-linked oligosaccharides. Fungal Genet Biol 42(9):773-90 SGD PMID 15993632
  3. Ye P, et al. (2005) Gene function prediction from congruent synthetic lethal interactions in yeast. Mol Syst Biol 1():2005.0026 SGD PMID 16729061

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