YER126C
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| Systematic name | YER126C |
| Gene name | NSA2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr V:414175..413390 |
Description of YER126C: Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis[1][2]
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Contents
Community Commentary
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Interactions
Genetic
YER126C is a suppressor of NOG1
Mutation type(s): overexpression, Thermosensitive
[3] [4]
Two Hybrid
Two Hybrid interaction with NOG1
[3] [4]
Protein Details
Protein Degradation
Nsa2 is unstable when large ribosomal subunit biogenesis is blocked upstream of this factor. [3] [4]
Protein Function/Process
required for the processing of ITS2 in 27SB pre-rRNAs. [3] [4]
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References
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- ↑ Horsey EW, et al. (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27 SGD PMID 15100437
- ↑ Harnpicharnchai P, et al. (2001) Composition and functional characterization of yeast 66S ribosome assembly intermediates. Mol Cell 8(3):505-15 SGD PMID 11583614
- ↑ 3.0 3.1 3.2 3.3 Lebreton A, et al. (2006) Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs. J Biol Chem 281(37):27099-108 SGD PMID 16861225
- ↑ 4.0 4.1 4.2 4.3 submitted by Alice Lebreton on 2006-08-01
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