YKL117W
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| Systematic name | YKL117W |
| Gene name | SBA1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:220324..220974 |
| Primary SGDID | S000001600 |
Description of YKL117W: Co-chaperone that binds to and regulates Hsp90 family chaperones; important for pp60v-src activity in yeast; homologous to the mammalian p23 proteins and like p23 can regulate telomerase activity[1][2][3]
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References
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- ↑ Bohen SP (1998) Genetic and biochemical analysis of p23 and ansamycin antibiotics in the function of Hsp90-dependent signaling proteins. Mol Cell Biol 18(6):3330-9 SGD PMID 9584173
- ↑ Fang Y, et al. (1998) SBA1 encodes a yeast hsp90 cochaperone that is homologous to vertebrate p23 proteins. Mol Cell Biol 18(7):3727-34 SGD PMID 9632755
- ↑ Toogun OA, et al. (2007) The p23 molecular chaperone promotes functional telomerase complexes through DNA dissociation. Proc Natl Acad Sci U S A 104(14):5765-70 SGD PMID 17389357
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