YKL025C

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Systematic name YKL025C
Gene name PAN3
Aliases ECM35
Feature type ORF, Verified
Coordinates Chr XI:392279..390240
Primary SGDID S000001508


Description of YKL025C: Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex, which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes[1][2][3]




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References

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  1. Brown CE and Sachs AB (1998) Poly(A) tail length control in Saccharomyces cerevisiae occurs by message-specific deadenylation. Mol Cell Biol 18(11):6548-59 SGD PMID 9774670
  2. Brown CE, et al. (1996) PAN3 encodes a subunit of the Pab1p-dependent poly(A) nuclease in Saccharomyces cerevisiae. Mol Cell Biol 16(10):5744-53 SGD PMID 8816488
  3. Hammet A, et al. (2002) Posttranscriptional regulation of the RAD5 DNA repair gene by the Dun1 kinase and the Pan2-Pan3 poly(A)-nuclease complex contributes to survival of replication blocks. J Biol Chem 277(25):22469-74 SGD PMID 11953437

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