YHR058C

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Systematic name YHR058C
Gene name MED6
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:219884..218997
Primary SGDID S000001100


Description of YHR058C: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation[1][2][3][4]




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References

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  1. Guglielmi B, et al. (2004) A high resolution protein interaction map of the yeast Mediator complex. Nucleic Acids Res 32(18):5379-91 SGD PMID 15477388
  2. Kornberg RD (2005) Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 30(5):235-9 SGD PMID 15896740
  3. Lee YC, et al. (1997) A transcriptional mediator protein that is required for activation of many RNA polymerase II promoters and is conserved from yeast to humans. Mol Cell Biol 17(8):4622-32 SGD PMID 9234719
  4. Myers LC, et al. (1998) The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain. Genes Dev 12(1):45-54 SGD PMID 9420330

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