YOR243C

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Systematic name YOR243C
Gene name PUS7
Aliases
Feature type ORF, Verified
Coordinates Chr XV:792242..790212
Primary SGDID S000005769


Description of YOR243C: Pseudouridine synthase, catalyzes pseudouridylation at positions 35 and 56 in U2 snRNA, position 50 in 5S rRNA, position 13 in cytoplasmic tRNAs, and position 35 in pre-tRNA(Tyr); conserved in archaea, vertebrates, and some bacteria[1][2][3][4]




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References

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  1. Behm-Ansmant I, et al. (2003) The Saccharomyces cerevisiae U2 snRNA:pseudouridine-synthase Pus7p is a novel multisite-multisubstrate RNA:Psi-synthase also acting on tRNAs. RNA 9(11):1371-82 SGD PMID 14561887
  2. Decatur WA and Schnare MN (2008) Different mechanisms for Pseudouridine formation in yeast 5S and 5.8S rRNAs. Mol Cell Biol 28(10):3089-100 SGD PMID 18332121
  3. Ma X, et al. (2003) Pseudouridylation (Psi) of U2 snRNA in S. cerevisiae is catalyzed by an RNA-independent mechanism. EMBO J 22(8):1889-97 SGD PMID 12682021
  4. Wu G, et al. (2011) U2 snRNA is inducibly pseudouridylated at novel sites by Pus7p and snR81 RNP. EMBO J 30(1):79-89 SGD PMID 21131909

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