YDL006W
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| Systematic name | YDL006W |
| Gene name | PTC1 |
| Aliases | CWH47, KCS2, TPD1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:439906..440751 |
Description of YDL006W: Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by dephosphorylating Hog1p; mutation delays mitochondrial inheritance; deletion reveals defects in precursor tRNA splicing, sporulation and cell separation[1][2][3][4][5]
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References
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- ↑ Warmka J, et al. (2001) Ptc1, a type 2C Ser/Thr phosphatase, inactivates the HOG pathway by dephosphorylating the mitogen-activated protein kinase Hog1. Mol Cell Biol 21(1):51-60 SGD PMID 11113180
- ↑ Roeder AD, et al. (1998) Mitochondrial inheritance is delayed in Saccharomyces cerevisiae cells lacking the serine/threonine phosphatase PTC1. Mol Biol Cell 9(4):917-30 SGD PMID 9529388
- ↑ Maeda T, et al. (1994) A two-component system that regulates an osmosensing MAP kinase cascade in yeast. Nature 369(6477):242-5 SGD PMID 8183345
- ↑ van Zyl WH, et al. (1989) A general screen for mutant of Saccharomyces cerevisiae deficient in tRNA biosynthesis. Genetics 123(1):55-68 SGD PMID 2680757
- ↑ Robinson MK, et al. (1994) TPD1 of Saccharomyces cerevisiae encodes a protein phosphatase 2C-like activity implicated in tRNA splicing and cell separation. Mol Cell Biol 14(6):3634-45 SGD PMID 8196609
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