YBR252W
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Systematic name | YBR252W |
Gene name | DUT1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr II:722606..723049 |
Description of YBR252W: dUTPase, catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability[1][2][3]
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References
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- ↑ Guillet M, et al. (2006) dUTPase activity is critical to maintain genetic stability in Saccharomyces cerevisiae. Nucleic Acids Res 34(7):2056-66 SGD PMID 16617146
- ↑ Godsen, M.H, et al. (1986) The isolation of dUTPase gene (DUT1) from Saccharomyces cerevisiae. Yeast 2:121 SGD PMID
- ↑ Gadsden MH, et al. (1993) dUTP pyrophosphatase is an essential enzyme in Saccharomyces cerevisiae. EMBO J 12(11):4425-31 SGD PMID 8223452
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