YKL217W

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Systematic name YKL217W
Gene name JEN1
Aliases
Feature type ORF, Verified
Coordinates Chr XI:22234..24084
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Description of YKL217W: Lactate transporter, required for uptake of lactate and pyruvate; expression is derepressed by transcriptional activator Cat8p under nonfermentative growth conditions, and repressed in the presence of glucose, fructose, and mannose[1][2][3]



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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically lower expression in sulfur limited chemostat cultures versus sulfur excess. [4] [5]


Other Topic: expression

Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [4] [5]


References

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  1. Akita O, et al. (2000) Transport of pyruvate in Saccharomyces cerevisiae and cloning of the gene encoded pyruvate permease. Biosci Biotechnol Biochem 64(5):980-4 SGD PMID 10879467
  2. Casal M, et al. (1999) The lactate-proton symport of Saccharomyces cerevisiae is encoded by JEN1. J Bacteriol 181(8):2620-3 SGD PMID 10198029
  3. Haurie V, et al. (2001) The transcriptional activator Cat8p provides a major contribution to the reprogramming of carbon metabolism during the diauxic shift in Saccharomyces cerevisiae. J Biol Chem 276(1):76-85 SGD PMID 11024040
  4. 4.0 4.1 Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  5. 5.0 5.1 submitted by Viktor Boer on 2003-07-25

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