YNL293W
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Systematic name | YNL293W |
Gene name | MSB3 |
Aliases | GYP3 |
Feature type | ORF, Verified |
Coordinates | Chr XIV:80640..82541 |
Primary SGDID | S000005237 |
Description of YNL293W: GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exocytosis via its action on Sec4p, also required for proper actin organization; similar to Msb4p; both Msb3p and Msb4p localize to sites of polarized growth[1][2][3]
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References
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- ↑ Albert S and Gallwitz D (1999) Two new members of a family of Ypt/Rab GTPase activating proteins. Promiscuity of substrate recognition. J Biol Chem 274(47):33186-9 SGD PMID 10559187
- ↑ Bach S, et al. (2000) Co-deletion of the MSB3 and MSB4 coding regions affects bipolar budding and perturbs the organization of the actin cytoskeleton. Yeast 16(11):1015-23 SGD PMID 10923023
- ↑ Gao XD, et al. (2003) The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization. J Cell Biol 162(4):635-46 SGD PMID 12913108
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