YLR197W
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Systematic name | YLR197W |
Gene name | NOP56 |
Aliases | SIK1 |
Feature type | ORF, Verified |
Coordinates | Chr XII:546099..547613 |
Primary SGDID | S000004187 |
Description of YLR197W: Essential evolutionarily-conserved nucleolar protein component of the box C/D snoRNP complexes that direct 2'-O-methylation of pre-rRNA during its maturation; overexpression causes spindle orientation defects[1][2][3][4]
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References
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- ↑ Bogomolnaya LM, et al. (2004) A new enrichment approach identifies genes that alter cell cycle progression in Saccharomyces cerevisiae. Curr Genet 45(6):350-9 SGD PMID 15022016
- ↑ Gautier T, et al. (1997) Nucleolar KKE/D repeat proteins Nop56p and Nop58p interact with Nop1p and are required for ribosome biogenesis. Mol Cell Biol 17(12):7088-98 SGD PMID 9372940
- ↑ Hayano T, et al. (2003) Proteomic analysis of human Nop56p-associated pre-ribosomal ribonucleoprotein complexes. Possible link between Nop56p and the nucleolar protein treacle responsible for Treacher Collins syndrome. J Biol Chem 278(36):34309-19 SGD PMID 12777385
- ↑ Lafontaine DL and Tollervey D (2000) Synthesis and assembly of the box C+D small nucleolar RNPs. Mol Cell Biol 20(8):2650-9 SGD PMID 10733567
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