YHR204W
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| Systematic name | YHR204W |
| Gene name | MNL1 |
| Aliases | HTM1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:506319..508709 |
| Primary SGDID | S000001247 |
Description of YHR204W: alpha-1,2-specific exomannosidase of the endoplasmic reticulum that generates a Man7GlcNac2 oligosaccharide signal on glycoproteins destined for ubiquitin-proteasome degradation[1][2][3]
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Contents
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References
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- ↑ Clerc S, et al. (2009) Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum. J Cell Biol 184(1):159-72 SGD PMID 19124653
- ↑ Jakob CA, et al. (2001) Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast. EMBO Rep 2(5):423-30 SGD PMID 11375935
- ↑ Nakatsukasa K, et al. (2001) Mnl1p, an alpha -mannosidase-like protein in yeast Saccharomyces cerevisiae, is required for endoplasmic reticulum-associated degradation of glycoproteins. J Biol Chem 276(12):8635-8 SGD PMID 11254655
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