YCL043C

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Systematic name YCL043C
Gene name PDI1
Aliases MFP1, TRG1
Feature type ORF, Verified
Coordinates Chr III:50221..48653
Primary SGDID S000000548


Description of YCL043C: Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds[1][2][3][4]




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References

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  1. Farquhar R, et al. (1991) Protein disulfide isomerase is essential for viability in Saccharomyces cerevisiae. Gene 108(1):81-9 SGD PMID 1761235
  2. Laboissiere MC, et al. (1995) The essential function of protein-disulfide isomerase is to unscramble non-native disulfide bonds. J Biol Chem 270(47):28006-9 SGD PMID 7499282
  3. Noiva R and Lennarz WJ (1992) Protein disulfide isomerase. A multifunctional protein resident in the lumen of the endoplasmic reticulum. J Biol Chem 267(6):3553-6 SGD PMID 1740407
  4. Sevier CS, et al. (2001) A flavoprotein oxidase defines a new endoplasmic reticulum pathway for biosynthetic disulphide bond formation. Nat Cell Biol 3(10):874-82 SGD PMID 11584268

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