YNL141W

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Systematic name YNL141W
Gene name AAH1
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:359598..360641
Primary SGDID S000005085


Description of YNL141W: Adenine deaminase (adenine aminohydrolase), converts adenine to hypoxanthine; involved in purine salvage; transcriptionally regulated by nutrient levels and growth phase; Aah1p degraded upon entry into quiescence via SCF and the proteasome[1][2][3]




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References

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  1. Woods RA, et al. (1984) Adenine phosphoribosyltransferase mutants in Saccharomyces cerevisiae. J Gen Microbiol 130(10):2629-37 SGD PMID 6392474
  2. Guetsova ML, et al. (1997) The isolation and characterization of Saccharomyces cerevisiae mutants that constitutively express purine biosynthetic genes. Genetics 147(2):383-97 SGD PMID 9335580
  3. Escusa S, et al. (2006) Proteasome- and SCF-dependent degradation of yeast adenine deaminase upon transition from proliferation to quiescence requires a new F-box protein named Saf1p. Mol Microbiol 60(4):1014-25 SGD PMID 16677311

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