YJL038C

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Systematic name YJL038C
Gene name LOH1
Aliases OSW4
Feature type ORF, Verified
Coordinates Chr X:375768..375109
Primary SGDID S000003575


Description of YJL038C: Protein of unknown function with proposed role in maintenance of genome integrity; deletion mutant displays elevated rates of LOH; induced during sporulation; repressed during vegetative growth by Sum1p and Hst1p; sequence similar to IRC1[1][2][3]




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References

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  1. Chu S, et al. (1998) The transcriptional program of sporulation in budding yeast. Science 282(5389):699-705 SGD PMID 9784122
  2. McCord R, et al. (2003) Rfm1, a novel tethering factor required to recruit the Hst1 histone deacetylase for repression of middle sporulation genes. Mol Cell Biol 23(6):2009-16 SGD PMID 12612074
  3. Andersen MP, et al. (2008) A Genetic Screen for Increased Loss of Heterozygosity in Saccharomyces cerevisiae. Genetics 179(3):1179-95 SGD PMID 18562670

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