YPL203W
Share your knowledge...Edit this entry!
| Systematic name | YPL203W | |
| Gene name | TPK2 | |
| Aliases | PKA2, PKA3, YKR1 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr XVI:166255..167397 | |
| Don't edit this box! It's automatically regenerated, and edits will be lost when the update script runs. | ||
Description of YPL203W: Subunit of cytoplasmic cAMP-dependent protein kinase, which contains redundant catalytic subunits Tpk1p, Tpk2p, and Tpk3p and regulatory subunit Bcy1p; promotes vegetative growth in response to nutrients; activates filamentous growth[1][2][3][4]
Interactions
Genetic
Strain Background: S288C, W303, industrial
Genetic interaction with ATF1
Mutation type(s): deletion/partial inactivating
ATF1 is transcriptionally induced by glucose and sucrose. This regulation depends on Ras/cAMP/PKA signaling. Long-term expression of ATF1 requires both a fermentable carbon source and a nitrogen source. This regulation depends on FGM signaling. [5] [6]
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Interactions
Genetic
Strain Background: S288C, W303, industrial
Genetic interaction with ATF1
Mutation type(s): deletion/partial inactivating
ATF1 is transcriptionally induced by glucose and sucrose. This regulation depends on Ras/cAMP/PKA signaling. Long-term expression of ATF1 requires both a fermentable carbon source and a nitrogen source. This regulation depends on FGM signaling. [5] [6]
References
See Help:References on how to add references
- ↑ Pan X and Heitman J (1999) Cyclic AMP-dependent protein kinase regulates pseudohyphal differentiation in Saccharomyces cerevisiae. Mol Cell Biol 19(7):4874-87 SGD PMID 10373537
- ↑ Toda T, et al. (1987) Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Mol Cell Biol 7(4):1371-7 SGD PMID 3037314
- ↑ Ordiz I, et al. (1996) Glucose-induced inactivation of isocitrate lyase in Saccharomyces cerevisiae is mediated by the cAMP-dependent protein kinase catalytic subunits Tpk1 and Tpk2. FEBS Lett 385(1-2):43-6 SGD PMID 8641464
- ↑ Toda T, et al. (1987) Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell 50(2):277-87 SGD PMID 3036373
- ↑ 5.0 5.1 Verstrepen KJ, et al. (2003) The Saccharomyces cerevisiae alcohol acetyl transferase gene ATF1 is a target of the cAMP/PKA and FGM nutrient-signalling pathways. FEMS Yeast Res 4(3):285-96 SGD PMID 14654433
- ↑ 6.0 6.1 submitted by Kevin J Verstrepen on 2004-03-11
See Help:Categories on how to add the wiki page for this gene to a Category
