YKR010C
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| Systematic name | YKR010C |
| Gene name | TOF2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:460882..458567 |
| Primary SGDID | S000001718 |
Description of YKR010C: Protein required for rDNA silencing and mitotic rDNA condensation; stimulates Cdc14p phosphatase activity and may function to coordinate the release of Cdc14p during anaphase; displays synthetic genetic interactions with TOP1, HPR1 and YCS4[1][2][3][4][5]
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References
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- ↑ Park H and Sternglanz R (1999) Identification and characterization of the genes for two topoisomerase I-interacting proteins from Saccharomyces cerevisiae. Yeast 15(1):35-41 SGD PMID 10028183
- ↑ Zuniga S, et al. (1999) Deletion of 24 open reading frames from chromosome XI from Saccharomyces cerevisiae and phenotypic analysis of the deletants. Gene 233(1-2):141-50 SGD PMID 10375630
- ↑ Huang J, et al. (2006) Inhibition of homologous recombination by a cohesin-associated clamp complex recruited to the rDNA recombination enhancer. Genes Dev 20(20):2887-901 SGD PMID 17043313
- ↑ Geil C, et al. (2008) A nucleolus-localized activator of Cdc14 phosphatase supports rDNA segregation in yeast mitosis. Curr Biol 18(13):1001-5 SGD PMID 18595708
- ↑ Waples WG, et al. (2009) Putting the Brake on FEAR: Tof2 Promotes the Biphasic Release of Cdc14 Phosphatase during Mitotic Exit. Mol Biol Cell 20(1):245-55 SGD PMID 18923139
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