YNR026C

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Systematic name YNR026C
Gene name SEC12
Aliases SED2
Feature type ORF, Verified
Coordinates Chr XIV:674691..673276
Primary SGDID S000005309


Description of YNR026C: Guanine nucleotide exchange factor (GEF); glycosylated integral membrane protein of the endoplasmic reticulum, important for the initiation of transport vesicle budding from the endoplasmic reticulum through activation of the GTPase Sar1p[1][2]




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References

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  1. Barlowe C and Schekman R (1993) SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER. Nature 365(6444):347-9 SGD PMID 8377826
  2. d'Enfert C, et al. (1991) Sec12p-dependent membrane binding of the small GTP-binding protein Sar1p promotes formation of transport vesicles from the ER. J Cell Biol 114(4):663-70 SGD PMID 1907973

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