YNL227C

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Systematic name YNL227C
Gene name JJJ1
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:222432..220660
Primary SGDID S000005171


Description of YNL227C: Co-chaperone that stimulates the ATPase activity of Ssa1p, required for a late step of ribosome biogenesis; associated with the cytosolic large ribosomal subunit; contains a J-domain; mutation causes defects in fluid-phase endocytosis[1][2][3]




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References

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  1. Wiederkehr A, et al. (2001) Identification and characterization of Saccharomyces cerevisiae mutants defective in fluid-phase endocytosis. Yeast 18(8):759-73 SGD PMID 11378903
  2. Walsh P, et al. (2004) The J-protein family: modulating protein assembly, disassembly and translocation. EMBO Rep 5(6):567-71 SGD PMID 15170475
  3. Meyer AE, et al. (2007) The specialized cytosolic J-protein, Jjj1, functions in 60S ribosomal subunit biogenesis. Proc Natl Acad Sci U S A 104(5):1558-63 SGD PMID 17242366

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