YMR260C

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Systematic name YMR260C
Gene name TIF11
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:789838..789377
Primary SGDID S000004873


Description of YMR260C: Translation initiation factor eIF1A, essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3[1][2][3]




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References

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  1. Wei CL, et al. (1995) Characterization of yeast translation initiation factor 1A and cloning of its essential gene. J Biol Chem 270(39):22788-94 SGD PMID 7559407
  2. Maag D, et al. (2005) A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codon. Mol Cell 17(2):265-75 SGD PMID 15664195
  3. Olsen DS, et al. (2003) Domains of eIF1A that mediate binding to eIF2, eIF3 and eIF5B and promote ternary complex recruitment in vivo. EMBO J 22(2):193-204 SGD PMID 12514125

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