YJR084W

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Systematic name YJR084W
Gene name CSN12
Aliases
Feature type ORF, Verified
Coordinates Chr X:583725..584996
Primary SGDID S000003844


Description of YJR084W: Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in mRNA splicing and adaptation to pheromone signaling[1][2][3]




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References

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  1. Wee S, et al. (2002) Conservation of the COP9/signalosome in budding yeast. BMC Genet 3:15 SGD PMID 12186635
  2. Maytal-Kivity V, et al. (2002) COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep 3(12):1215-21 SGD PMID 12446563
  3. Wilmes GM, et al. (2008) A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing. Mol Cell 32(5):735-46 SGD PMID 19061648

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