YJR069C
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Systematic name | YJR069C |
Gene name | HAM1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr X:569391..568798 |
Primary SGDID | S000003830 |
Description of YJR069C: Conserved protein with deoxyribonucleoside triphosphate pyrophosphohydrolase activity, mediates exclusion of noncanonical purines from deoxyribonucleoside triphosphate pools; mutant is sensitive to the base analog 6-N-hydroxylaminopurine[1][2]
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References
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- ↑ Noskov VN, et al. (1996) HAM1, the gene controlling 6-N-hydroxylaminopurine sensitivity and mutagenesis in the yeast Saccharomyces cerevisiae. Yeast 12(1):17-29 SGD PMID 8789257
- ↑ Burgis NE and Cunningham RP (2007) Substrate specificity of RdgB protein, a deoxyribonucleoside triphosphate pyrophosphohydrolase. J Biol Chem 282(6):3531-8 SGD PMID 17090528
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