YGL211W

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Systematic name YGL211W
Gene name NCS6
Aliases TUC1, YGL210W-A
Feature type ORF, Verified
Coordinates Chr VII:92516..93595
Primary SGDID S000003179


Description of YGL211W: Protein required for thiolation of the uridine at the wobble position of Gln, Lys, and Glu tRNAs; has a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae[1][2][3]




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References

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  1. Kushner DB, et al. (2003) Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Proc Natl Acad Sci U S A 100(26):15764-9 SGD PMID 14671320
  2. Goehring AS, et al. (2003) Urmylation: a ubiquitin-like pathway that functions during invasive growth and budding in yeast. Mol Biol Cell 14(11):4329-41 SGD PMID 14551258
  3. Bjork GR, et al. (2007) A conserved modified wobble nucleoside (mcm5s2U) in lysyl-tRNA is required for viability in yeast. RNA 13(8):1245-55 SGD PMID 17592039

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