YGL087C

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Systematic name YGL087C
Gene name MMS2
Aliases
Feature type ORF, Verified
Coordinates Chr VII:346907..346409
Primary SGDID S000003055


Description of YGL087C: Ubiquitin-conjugating enzyme variant involved in error-free postreplication repair; forms a heteromeric complex with Ubc13p, an active ubiquitin-conjugating enzyme; cooperates with chromatin-associated RING finger proteins, Rad18p and Rad5p[1][2][3][4]




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References

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  1. Ulrich HD and Jentsch S (2000) Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair. EMBO J 19(13):3388-97 SGD PMID 10880451
  2. Broomfield S, et al. (1998) MMS2, encoding a ubiquitin-conjugating-enzyme-like protein, is a member of the yeast error-free postreplication repair pathway. Proc Natl Acad Sci U S A 95(10):5678-83 SGD PMID 9576943
  3. Hofmann RM and Pickart CM (1999) Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair. Cell 96(5):645-53 SGD PMID 10089880
  4. Ulrich HD (2003) Protein-protein interactions within an E2-RING finger complex. Implications for ubiquitin-dependent DNA damage repair. J Biol Chem 278(9):7051-8 SGD PMID 12496280

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