YDR363W
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| Systematic name | YDR363W |
| Gene name | ESC2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1199176..1200546 |
| Primary SGDID | S000002771 |
Description of YDR363W: Protein involved in silencing; may recruit or stabilize Sir proteins; role in Rad51-dependent homologous recombination repair and intra S-phase DNA damage checkpoint; member of the RENi (Rad60-Esc2-Nip45) family of SUMO-like domain proteins[1][2][3][4]
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References
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- ↑ Dhillon N and Kamakaka RT (2000) A histone variant, Htz1p, and a Sir1p-like protein, Esc2p, mediate silencing at HMR. Mol Cell 6(4):769-80 SGD PMID 11090616
- ↑ Cuperus G and Shore D (2002) Restoration of silencing in Saccharomyces cerevisiae by tethering of a novel Sir2-interacting protein, Esc8. Genetics 162(2):633-45 SGD PMID 12399377
- ↑ Novatchkova M, et al. (2005) Proteins with two SUMO-like domains in chromatin-associated complexes: the RENi (Rad60-Esc2-NIP45) family. BMC Bioinformatics 6:22 SGD PMID 15698469
- ↑ Mankouri HW, et al. (2009) Esc2 and Sgs1 act in functionally distinct branches of the homologous recombination repair pathway in Saccharomyces cerevisiae. Mol Biol Cell 20(6):1683-94 SGD PMID 19158388
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