YKR031C

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Systematic name YKR031C
Gene name SPO14
Aliases PLD1
Feature type ORF, Verified
Coordinates Chr XI:506037..500986
Primary SGDID S000001739


Description of YKR031C: Phospholipase D, catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid; involved in Sec14p-independent secretion; required for meiosis and spore formation; differently regulated in secretion and meiosis[1][2][3][4]




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References

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  1. Xie Z, et al. (1998) Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects. Proc Natl Acad Sci U S A 95(21):12346-51 SGD PMID 9770489
  2. Sreenivas A, et al. (1998) A role for phospholipase D (Pld1p) in growth, secretion, and regulation of membrane lipid synthesis in yeast. J Biol Chem 273(27):16635-8 SGD PMID 9642212
  3. Rudge SA, et al. (1998) Relocalization of phospholipase D activity mediates membrane formation during meiosis. J Cell Biol 140(1):81-90 SGD PMID 9425156
  4. Rudge SA, et al. (2002) Differential regulation of Saccharomyces cerevisiae phospholipase D in sporulation and Sec14-independent secretion. Genetics 160(4):1353-61 SGD PMID 11973292

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