YER021W

From SGD-Wiki
Revision as of 14:05, 31 March 2009 by SGDwikiBot (talk | contribs) (Automated import of articles)
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YER021W
Gene name RPN3
Aliases SUN2
Feature type ORF, Verified
Coordinates Chr V:196947..198518
Primary SGDID S000000823


Description of YER021W: Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to the p58 subunit of the human 26S proteasome; temperature-sensitive alleles cause metaphase arrest, suggesting a role for the proteasome in cell cycle control[1][2][3][4]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!




<protect>

References

See Help:References on how to add references

  1. Glickman MH, et al. (1998) A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3. Cell 94(5):615-23 SGD PMID 9741626
  2. Bailly E and Reed SI (1999) Functional characterization of rpn3 uncovers a distinct 19S proteasomal subunit requirement for ubiquitin-dependent proteolysis of cell cycle regulatory proteins in budding yeast. Mol Cell Biol 19(10):6872-90 SGD PMID 10490625
  3. Kominami K, et al. (1997) Yeast counterparts of subunits S5a and p58 (S3) of the human 26S proteasome are encoded by two multicopy suppressors of nin1-1. Mol Biol Cell 8(1):171-87 SGD PMID 9017604
  4. Kaiser P, et al. (1999) Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets. Genes Dev 13(9):1190-202 SGD PMID 10323869

See Help:Categories on how to add the wiki page for this gene to a Category </protect>