YLR135W

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Systematic name YLR135W
Gene name SLX4
Aliases
Feature type ORF, Verified
Coordinates Chr XII:413282..415528
Primary SGDID S000004125


Description of YLR135W: Endonuclease involved in processing DNA during recombination and repair; cleaves branched structures in a complex with Slx1p; involved in Rad1p/Rad10p-dependent removal of 3'-nonhomologous tails during DSBR via single-strand annealing[1][2]




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References

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  1. Li F, et al. (2008) Microarray-based genetic screen defines SAW1, a gene required for Rad1/Rad10-dependent processing of recombination intermediates. Mol Cell 30(3):325-35 SGD PMID 18471978
  2. Fricke WM and Brill SJ (2003) Slx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3. Genes Dev 17(14):1768-78 SGD PMID 12832395

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