YNL023C

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Systematic name YNL023C
Gene name FAP1
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:591161..588264
Primary SGDID S000004968


Description of YNL023C: Protein that binds to Fpr1p, conferring rapamycin resistance by competing with rapamycin for Fpr1p binding; accumulates in the nucleus upon treatment of cells with rapamycin; has similarity to D. melanogaster shuttle craft and human NFX1[1]




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References

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  1. Kunz J, et al. (2000) FAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast. Mol Microbiol 37(6):1480-93 SGD PMID 10998178

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