YDR120C

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Systematic name YDR120C
Gene name TRM1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:693259..691547
Primary SGDID S000002527


Description of YDR120C: tRNA methyltransferase, localizes to both the nucleus and mitochondrion to produce the modified base N2,N2-dimethylguanosine in tRNAs in both compartments[1][2]




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References

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  1. Rose AM, et al. (1992) Separate information required for nuclear and subnuclear localization: additional complexity in localizing an enzyme shared by mitochondria and nuclei. Mol Cell Biol 12(12):5652-8 SGD PMID 1448094
  2. Ellis SR, et al. (1986) Isolation and characterization of the TRM1 locus, a gene essential for the N2,N2-dimethylguanosine modification of both mitochondrial and cytoplasmic tRNA in Saccharomyces cerevisiae. J Biol Chem 261(21):9703-9 SGD PMID 2426253

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