YHR087W
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| Systematic name | YHR087W |
| Gene name | RTC3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:280822..281157 |
| Primary SGDID | S000001129 |
Description of YHR087W: Protein of unknown function involved in RNA metabolism; has structural similarity to SBDS, the human protein mutated in Shwachman-Diamond Syndrome (the yeast SBDS ortholog = SDO1); null mutation suppresses cdc13-1 temperature sensitivity[1][2][3][4]
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References
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- ↑ Shammas C, et al. (2005) Structural and mutational analysis of the SBDS protein family. Insight into the leukemia-associated Shwachman-Diamond Syndrome. J Biol Chem 280(19):19221-9 SGD PMID 15701631
- ↑ Savchenko A, et al. (2005) The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism. J Biol Chem 280(19):19213-20 SGD PMID 15701634
- ↑ Boocock GR, et al. (2006) Phylogeny, sequence conservation, and functional complementation of the SBDS protein family. Genomics 87(6):758-71 SGD PMID 16529906
- ↑ Addinall SG, et al. (2008) A Genomewide Suppressor and Enhancer Analysis of cdc13-1 Reveals Varied Cellular Processes Influencing Telomere Capping in Saccharomyces cerevisiae. Genetics 180(4):2251-66 SGD PMID 18845848
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