YGL050W

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Systematic name YGL050W
Gene name TYW3
Aliases
Feature type ORF, Verified
Coordinates Chr VII:405779..406600
Primary SGDID S000003018


Description of YGL050W: tRNA methyltransferase required for synthesis of wybutosine, a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions[1][2]




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References

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  1. Noma A, et al. (2006) Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA. EMBO J 25(10):2142-54 SGD PMID 16642040
  2. Noma A and Suzuki T (2006) Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis. Nucleic Acids Symp Ser (Oxf) (50):65-6 SGD PMID 17150819

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